As SAFC continues to settle into 2012, there is plenty of planning and development going on across the global SAFC network. Leading into the first big tradeshow of the year, Informex 2012 in New Orleans, LA, SAFC has been focused on introducing a new line of products that take quality and security of supply chain to another level. Below, Dave Backer, SAFC Director of Business Development and Marketing, discusses what the PharmaGrade product portfolio, means for SAFC customers and why it is relevant to the market.
Archive for the ‘Cell biology’ Category
SAFC’s Dave Backer Discusses the Full Line of SAFC PharmaGrade Products and Highlights the PharmaGrade MSX Product Capabilities
Friday, February 3rd, 2012LIVE from CPhI Worldwide: SAFC Announces Introduction of CHOZN GS Knockout CHO Line
Thursday, October 27th, 2011Following the introduction of the CHO cell line earlier this year in July, SAFC has just announced the release of a novel CHOZN® GS-/- Zinc Finger Nuclease (ZFN)- modified Chinese Hamster Ovary (CHO) cell line. Designed for use in the production of biopharmaceuticals, the new CHOZN GS-/- cell line is the first commercially available glutamine synthetase (GS) knockout CHO cell line proven to shorten bioproduction times in early development, enabling customers to enhance their speed-to-market and increase cost efficiency. Read more about it on Manufacturing Chemist by clicking here.
Pharma Magazine Feature: From DNA to Harvest: A Platform Approach to Improved Bio-Production
Wednesday, September 28th, 2011The September/October issue of Pharma Magazine features an article authored by Bruce Lehr, SAFC Director of Development and Kevin Kayser, SAFC Associate Director of Cell Engineering which discusses using a platform development and manufacturing strategy to control operations across biopharmaceutical projects. The article further discusses SAFC’s ZFN (Zinc Finger Nuclease) technology which allows for the isolation of genes for modification. Please take a moment to read the full story here.
SAFC to Present at BioProcess International China Conference
Friday, August 5th, 2011Join SAFC on August 22-23, 2011, at the Grand Hyatt Shanghai for the BioProcess International China Conference. The two-day program, hosted by IBC, is known for bringing together thought leaders and decision makers in biotechnology. SAFC will present on August 22nd as part of a dual track program format, focusing on Cell Culture and Cell Line Development and Product/Process Characterization to Improve Quality and Comparability.
News Alert: SAFC Extends Gene Editing Technology Platform with Readily-Available Zinc Finger Nuclease Products and Services
Wednesday, November 10th, 2010SAFC today announced an extension to Sigma-Aldrich’s proprietary CompoZr® Zinc Finger Nuclease (ZFN) platform that will expand the availability of ZFN-based technology to include off-the-shelf ZFNs and custom cell engineering services for use in the biopharmaceutical industry.
Life Science Leader: Zinc Fingers Point The Way Forwards
Wednesday, September 29th, 2010In October’s issue of Life Science Leader, Kevin Kayser, manager of the Cell Culture Engineering group at SAFC, gives an overview of Zinc Finger Nuclease (ZFN) technology, an area that has, since its introduction, helped facilitate rapid advances within the field of targeted genome editing.
ZFNs are custom-engineered fusion proteins that bind DNA in a targeted way to create double-stranded breaks at precise points, enabling the genome to be edited. Modifications, insertions or deletions can be made to the genome, a development that facilitates the rapid creation of genetically modified cell lines that give greater insight into genetic diseases and their associated pathway biologies. Such knowledge can be potentially used to develop therapeutic treatments for all manner of diseases and conditions that have identified genetic markers.
BioPharm International: SAFC’s Bruce Lehr and Bretta Erskine of EMD Millipore Discuss Cell Culture Media Trends
Monday, September 27th, 2010n the September supplement to BioPharm International, Bretta Erskine, manager of upstream technology and collaborations, EMD Millipore, and SAFC’s very own director of development, Bruce Lehr, discuss the issues of the day relating to cell culture media, including high cell density cell culture operations, animal-component–free media, raw materials origins and auditing, trends in chemically-defined media and fermentation in media production.
You can read the full Q&A here



